Propanoic acid, 3-(trimethylsilyl)-
3-(TRIMETHYLSILYL) PROPIONIC ACID
CAS: 5683-30-7
Molecular Formula: C6H14O2Si
Propanoic acid, 3-(trimethylsilyl)- - Names and Identifiers
Propanoic acid, 3-(trimethylsilyl)- - Physico-chemical Properties
| Molecular Formula | C6H14O2Si |
| Molar Mass | 146.26 |
| Density | 0.92 |
| Melting Point | 22 °C |
| Boling Point | 130 °C |
| Flash Point | 74°C |
| Specific Gravity | 0.92 |
| pKa | 4.98±0.10(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Sensitive | 1: no significant reaction with aqueous systems |
| Refractive Index | 1.4280 |
Propanoic acid, 3-(trimethylsilyl)- - Risk and Safety
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| TSCA | Yes |
Propanoic acid, 3-(trimethylsilyl)- - References
| EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
| Use | 3-trimethylsilylpropionic acid is a carboxylic acid. Carboxylic acids are important organic compounds, which are widely used in industry, agriculture, medicine and people's daily life. The oxidation of alcohols to acids is a fundamental and important chemical reaction in organic chemistry. In the industrial and pharmaceutical fields, the production of carboxylic acids is often obtained by oxidation. |
| preparation | add Fe(NO3)3 · 9H2O(40.5mg,0.1mmol) to a ML round-bottom bottle and DCE(4.0mL), followed by the addition of TEMPO(15.7mg,0.1mmol),KCl(7.8mg,0.1mmol), 3-trimethylsilylpropargyl alcohol (128.6mg,1.0mmol) and DCE(1.0). The round-bottom bottle is connected to the Air Balloon via a suction valve. The reaction was stirred at room temperature for 48 h until completion of the reaction as monitored by TLC (petroleum ether: ethyl acetate = 5:1). The reaction mixture was filtered through a short column of crude silica gel and rinsed with diethyl ether (75ml). After vacuum spin dry solvent, silica gel column chromatography (petroleum ether: ethyl acetate = 5:1) was purified to obtain 3-trimethylsilylpropiolic acid (92.9mg,65%)(petroleum ether: ethyl acetate = 5:1): 1). |
Last Update：2024-04-10 22:29:15
Supplier List
Product Name: 3-(TRIMETHYLSILYL) PROPIONIC ACID Visit Supplier Webpage Request for quotation
CAS: 5683-30-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 5683-30-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Product Name: 3-(TRIMETHYLSILYL) PROPIONIC ACID Visit Supplier Webpage Request for quotation
CAS: 5683-30-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 5683-30-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History